| ZFIN ID: ZDB-EXP-180621-4 |
Experiment Conditions Description: chemical treatment by environment: L-dopa, chemical treatment by environment: oxidopamine
| chemical treatment by environment: L-dopa |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | L-dopa |
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| Synonyms: | (-)-3-(3,4-dihydroxyphenyl)-L-alanine, (-)-dopa, (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid, 3,4-Dihydroxy-L-phenylalanine, 3,4-DIHYDROXYPHENYLALANINE, 3-Hydroxy-L-tyrosine, beta-(3,4-dihydroxyphenyl)-L-alanine, beta-(3,4-dihydroxyphenyl)alanine, Dihydroxy-L-phenylalanine, Dopar, L-beta-(3,4-Dihydroxyphenyl)alanine, L-DOPA, levodopa, levodopum |
| Definition: | An optically active form of dopa having L-configuration. Used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease |
| Ontology: | ChEBI [CHEBI:15765] ( EBI ) |
| chemical treatment by environment: oxidopamine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | oxidopamine |
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| Synonyms: | 2,4,5-trihydroxyphenethylamine, 5-(2-aminoethyl)benzene-1,2,4-triol, 6-hydroxydopamine, 6-OHDA, hydroxydopamine, oxidopamina, oxidopamine, oxidopaminum, topamine |
| Definition: | A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease). |
| Ontology: | ChEBI [CHEBI:78741] ( EBI ) |
| Publication: | Cronin et al., 2017 |
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