| ZFIN ID: ZDB-EXP-180620-8 |
Experiment Conditions Description: chemical treatment by environment: rasagiline, chemical treatment by environment: oxidopamine
| chemical treatment by environment: rasagiline |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | rasagiline |
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| Synonyms: | (1R)-N-(prop-2-yn-1-yl)indan-1-amine, (1R)-N-propargylindan-1-amine, (R)-indan-1-yl-prop-2-ynyl-amine, (R)-N-2-Propynyl-1-indanamine, RAS, rasagiline |
| Definition: | An indane that consists of 1-aminoindane bearing an N-propargyl substituent. A selective, irreversible monoamine oxidase-B inhibitor. |
| Ontology: | ChEBI [CHEBI:63620] ( EBI ) |
| chemical treatment by environment: oxidopamine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | oxidopamine |
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| Synonyms: | 2,4,5-trihydroxyphenethylamine, 5-(2-aminoethyl)benzene-1,2,4-triol, 6-hydroxydopamine, 6-OHDA, hydroxydopamine, oxidopamina, oxidopamine, oxidopaminum, topamine |
| Definition: | A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease). |
| Ontology: | ChEBI [CHEBI:78741] ( EBI ) |
| Publication: | Cronin et al., 2017 |
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