| ZFIN ID: ZDB-EXP-180201-12 |
Experiment Conditions Description: fasting, chemical treatment: AMPK activator PT 1
| fasting |
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| Name: | fasting |
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| Synonyms: | |
| Definition: | Limited food availability condition in which there is no food provided. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000114] |
| chemical treatment: AMPK activator PT 1 |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | AMPK activator PT 1 |
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| Synonyms: | 2-chloro-5-[(5-{[5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl]methylidene}-4-oxo-4,5-dihydro-1,3-thiazol-2-yl)amino]benzoic acid, 2-Chloro-5-[[5-[[5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-4-oxo-2-thiazolyl]amino]benzoic acid, PT 1 |
| Definition: | A member of the class of furans that in which the furan ring is substituted by a (2-amino-4-oxo-1,3-thiazol-5(4H)-ylidene)methyl group at position 2 and a 4,5-dimethyl-2-nitrophenyl group at position 5, and i which the amino substituent of the thiazolone has been substituted by a 3-carboxy-4-chlorophenyl group. It is a direct activator of the alpha-subunit of AMP-activated protein kinase (5' adenosine monophosphate-activated protein kinase, AMPK). |
| Ontology: | ChEBI [CHEBI:139579] ( EBI ) |
| Publication: | Gu et al., 2014 |
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