| ZFIN ID: ZDB-EXP-170706-3 |
Experiment Conditions Description: chemical treatment by injection: (S)-2-methyl-1-(4-methylisoquinoline-5-sulfonyl)-1,4-diazepane dihydrochloride
| chemical treatment by injection: (S)-2-methyl-1-(4-methylisoquinoline-5-sulfonyl)-1,4-diazepane dihydrochloride |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | (S)-2-methyl-1-(4-methylisoquinoline-5-sulfonyl)-1,4-diazepane dihydrochloride |
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| Synonyms: | 4-methyl-5-[(2S)-2-methyl-1,4-diazepane-1-sulfonyl]isoquinoline dihydrochloride, dimethyl fasudil dihydrochloride, H-1152 dihydrochloride, ROCK inhibitor |
| Definition: | A hydrochloride salt resulting from the reaction of (S)-2-methyl-1-(4-methylisoquinoline-5-sulfonyl)-1,4-diazepane with 2 mol eq. of hydrogen chloride. An ATP-competitive inhibitor of Rho kinase (ROCK). |
| Ontology: | ChEBI [CHEBI:137694] ( EBI ) |
| Publication: | Miranda-RodrÃguez et al., 2017 |
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