| ZFIN ID: ZDB-EXP-160921-3 |
Experiment Conditions Description: chemical treatment by diet: D-glucose, chemical treatment: diazoxide
| chemical treatment by diet: D-glucose |
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| Name: | chemical treatment by diet |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the diet. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000239] |
| chemical treatment: diazoxide |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | diazoxide |
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| Synonyms: | 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, Diazossido, Diazoxide, diazoxido, diazoxidum, Eudemine |
| Definition: | A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies. |
| Ontology: | ChEBI [CHEBI:4495] ( EBI ) |
| Publication: | Li et al., 2014 |
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