| ZFIN ID: ZDB-EXP-141211-8 |
Experiment Conditions Description: physical alteration: anatomical structure, chemical treatment: DAPT
| physical alteration: anatomical structure |
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| Name: | physical alteration |
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| Synonyms: | |
| Definition: | Experimental condition in which an anatomical structure, cell, or organ has sustained targeted physical change, usually through the use of an instrument. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000229] |
| Name: | anatomical structure |
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| Synonyms: | anatomical structures |
| Definition: | Zebrafish anatomical entity that has inherent 3D shape and is generated by coordinated expression of the organism's own genome. |
| Ontology: | Anatomy Ontology [ZFA:0000037] |
| chemical treatment: DAPT |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | DAPT |
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| Synonyms: | gamma-secretase inhibitor IX, GSI-IX, tert-butyl (2S)-({N-[(3,5-difluorophenyl)acetyl]-L-alanyl}amino)(phenyl)acetate, tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate |
| Definition: | A dipeptide consisting of alanylphenylglycine derivatised as a 3,5-difluorophenylacetamide at the amino terminal and a tert-butyl ester at the carboxy terminal. It is a gamma-secretase inhibitor. |
| Ontology: | ChEBI [CHEBI:86193] ( EBI ) |
| Publication: | Grotek et al., 2013 |
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