TALEN

TALEN2-stat3

ID

ZDB-TALEN-220929-1

Name

TALEN2-stat3

Previous Names

None

Target

stat3 (1)

Target Sequence 1

5' - AGTTGCAGCAGTT - 3'

Target Sequence 2

5' - AGGTGATACAGCTGCTCC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf3573	stat3
zf3574	stat3

Expression

Gene expression in Wild Types + TALEN2-stat3

No data available

Phenotype

Phenotype resulting from TALEN2-stat3

No data available

Phenotype of all Fish created by or utilizing TALEN2-stat3

Phenotype	Fish	Conditions	Figures
vertebral column increased curvature, abnormal	stat3^{zf3573/zf3573} (AB)	standard conditions	Fig. 3 from Xiong et al., 2017
vertebral column kinked, abnormal	stat3^{zf3573/zf3573} (AB)	standard conditions	Fig. 3 from Xiong et al., 2017
vertebral column asymmetrically curved, abnormal	stat3^{zf3573/zf3573} (AB)	standard conditions	Fig. 3 from Xiong et al., 2017
whole organism decreased size, abnormal	stat3^{zf3573/zf3573} (AB)	standard conditions	Fig. 3 from Xiong et al., 2017
vertebral column rotational curvature, abnormal	stat3^{zf3573/zf3573} (AB)	standard conditions	Fig. 3 from Xiong et al., 2017
bone tissue col27a1b expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 7 from Xiong et al., 2017
bone tissue col15a1b expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 7 from Xiong et al., 2017
dentary morphology, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 5 from Xiong et al., 2017
vertebral column increased curvature, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 3, Fig. 4, Fig. 5 from Xiong et al., 2017
bone tissue col1a2 expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 7 from Xiong et al., 2017
bone tissue igf1 expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 6 from Xiong et al., 2017
bone tissue il22 expression increased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 6 from Xiong et al., 2017
bone tissue col1a1a expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 7 from Xiong et al., 2017
bone tissue il34 expression increased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 6 from Xiong et al., 2017
bone tissue il6 expression increased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 6 from Xiong et al., 2017
bone tissue il11a expression increased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 6 from Xiong et al., 2017
mouth open, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 5 from Xiong et al., 2017
premaxilla morphology, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 5 from Xiong et al., 2017
bone tissue col8a1b expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 7 from Xiong et al., 2017
bone tissue il4 expression increased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 6 from Xiong et al., 2017
vertebra neural spine bent, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 5 from Xiong et al., 2017
bone tissue pomca expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 6 from Xiong et al., 2017
bone tissue col27a1a expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 7 from Xiong et al., 2017
bone tissue gh1 expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 6 from Xiong et al., 2017
bone tissue il1b expression increased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 6 from Xiong et al., 2017
bone tissue col1a1b expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 7 from Xiong et al., 2017
bone tissue il11b expression increased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 6 from Xiong et al., 2017
vertebral column rotational curvature, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 3, Fig. 4, Fig. 5 from Xiong et al., 2017
vertebral column kinked, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 3, Fig. 4, Fig. 5 from Xiong et al., 2017
vertebral column asymmetrically curved, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 3, Fig. 4, Fig. 5 from Xiong et al., 2017
whole organism decreased size, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 3 from Xiong et al., 2017
bone tissue col2a1a expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 7 from Xiong et al., 2017
ventral mandibular arch morphology, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 5 from Xiong et al., 2017
anguloarticular morphology, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 5 from Xiong et al., 2017
vertebral column joint dislocated, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 5 from Xiong et al., 2017
vertebra decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 5 from Xiong et al., 2017
bone tissue stat3 expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 6 from Xiong et al., 2017
bone tissue col9a1a expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 7 from Xiong et al., 2017
bone tissue col2a1b expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 7 from Xiong et al., 2017
bone tissue tgfb2 expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 6 from Xiong et al., 2017
bone tissue tgfb3 expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 6 from Xiong et al., 2017
bone tissue col10a1a expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 7 from Xiong et al., 2017
vertebral column joint fractured, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 5 from Xiong et al., 2017
bone tissue col8a2 expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 7 from Xiong et al., 2017
bone tissue col9a1b expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 7 from Xiong et al., 2017
bone tissue il26 expression increased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 6 from Xiong et al., 2017
bone tissue col9a2 expression decreased amount, abnormal	stat3^{zf3574/zf3574} (AB)	standard conditions	Fig. 7 from Xiong et al., 2017

Citations