TALEN

TALEN1-lamp2

ID

ZDB-TALEN-200127-2

Name

TALEN1-lamp2

Previous Names

None

Target

lamp2 (1)

Target Sequence 1

5' - TGACATCACCACTGCCCT - 3'

Target Sequence 2

5' - TAGGGGGAGGTTGGCTGT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
xu082	lamp2

Expression

Gene expression in Wild Types + TALEN1-lamp2

No data available

Phenotype

Phenotype resulting from TALEN1-lamp2

No data available

Phenotype of all Fish created by or utilizing TALEN1-lamp2

Phenotype	Fish	Conditions	Figures
cardiac muscle cell has extra parts of type cardiac muscle cell autophagosome, abnormal	lamp2^xu082/xu082 (WIK)	standard conditions	Fig. 2 from Dvornikov et al., 2019
cardiac muscle macroautophagy process quality, abnormal	lamp2^xu082/xu082 (WIK)	standard conditions	Fig. 2 from Dvornikov et al., 2019
heart contraction process quality, abnormal	lamp2^xu082/xu082 (WIK)	standard conditions	Fig. 3, Fig. 5 from Dvornikov et al., 2019
heart nppa expression increased amount, abnormal	lamp2^xu082/xu082 (WIK)	standard conditions	Fig. 3 from Dvornikov et al., 2019
skeletal muscle TOR signaling increased process quality, abnormal	lamp2^xu082/xu082 (WIK)	standard conditions	Fig. 2 from Dvornikov et al., 2019
whole organism decreased life span, abnormal	lamp2^xu082/xu082 (WIK)	standard conditions	Fig. 1 from Dvornikov et al., 2019
trabecular layer has extra parts of type cardiac muscle cell, abnormal	lamp2^xu082/xu082 (WIK)	standard conditions	Fig. 3 from Dvornikov et al., 2019
trabecular layer of the atrium increased thickness, abnormal	lamp2^xu082/xu082 (WIK)	standard conditions	Fig. 4 from Dvornikov et al., 2019
heart myh7 expression decreased amount, abnormal	lamp2^xu082/xu082 (WIK)	standard conditions	Fig. 3 from Dvornikov et al., 2019
whole organism lamp2 expression decreased amount, abnormal	lamp2^xu082/xu082 (WIK)	standard conditions	Fig. 1 from Dvornikov et al., 2019
atrium cardiac conduction system development process quality, abnormal	lamp2^xu082/xu082 (WIK)	standard conditions	Fig. 4 from Dvornikov et al., 2019
cardiac ventricle cardiac myofibril increased contractility, abnormal	lamp2^xu082/xu082 (WIK)	standard conditions	Fig. 6 from Dvornikov et al., 2019
atrium increased area, abnormal	lamp2^xu082/xu082 (WIK)	standard conditions	Fig. 4 from Dvornikov et al., 2019
regulation of heart contraction decreased process quality, abnormal	lamp2^xu082/xu082 (WIK)	standard conditions	Fig. 5 from Dvornikov et al., 2019
cardiac ventricle cardiac muscle cell contraction increased process quality, abnormal	lamp2^xu082/xu082 (WIK)	standard conditions	Fig. 6 from Dvornikov et al., 2019
heart obtuse, abnormal	lamp2^xu082/xu082 (WIK)	standard conditions	Fig. 3 from Dvornikov et al., 2019
whole organism decreased weight, abnormal	lamp2^xu082/xu082 (WIK)	standard conditions	Fig. 1 from Dvornikov et al., 2019
swimming decreased occurrence, abnormal	lamp2^xu082/xu082 (WIK)	standard conditions	Fig. 1 from Dvornikov et al., 2019
heart contraction process quality, ameliorated	lamp2^xu082/xu082; mtor^xu015Gt/+ (WIK)	standard conditions	Fig. 5 from Dvornikov et al., 2019
regulation of heart contraction process quality, ameliorated	lamp2^xu082/xu082; mtor^xu015Gt/+ (WIK)	standard conditions	Fig. 5 from Dvornikov et al., 2019
cardiac ventricle cardiac muscle cell contraction process quality, ameliorated	lamp2^xu082/xu082; mtor^xu015Gt/+ (WIK)	standard conditions	Fig. 6 from Dvornikov et al., 2019
cardiac ventricle cardiac myofibril contractility, ameliorated	lamp2^xu082/xu082; mtor^xu015Gt/+ (WIK)	standard conditions	Fig. 6 from Dvornikov et al., 2019

Citations