TALEN

TALEN3-epas1b

ID

ZDB-TALEN-180921-1

Name

TALEN3-epas1b

Previous Names

None

Target

epas1b (1)

Target Sequence 1

5' - TGTTTGTGCTGTATTGCAGGCT - 3'

Target Sequence 2

5' - TGAGTCTGTCTGCATCTGTCAT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

This TALEN was designed based on sequence from the AB strain which differs from the TU strain used in Ensembl. ATGACAGATGGAGACAGACTCA - (sequence from AB), ATGACAGATGCAGACAGACTCA (sequence from Ensembl)

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
bns232	epas1b

Expression

Gene expression in Wild Types + TALEN3-epas1b

No data available

Phenotype

Phenotype resulting from TALEN3-epas1b

No data available

Phenotype of all Fish created by or utilizing TALEN3-epas1b

Phenotype	Fish	Conditions	Figures
whole organism runx1 expression decreased amount, abnormal	epas1a^{bns231/bns231}; epas1b^{bns232/bns232}	standard conditions	Fig. 4 from Gerri et al., 2018
whole organism gata2b expression decreased amount, abnormal	epas1a^{bns231/bns231}; epas1b^{bns232/bns232}	control	Fig. 5 from Gerri et al., 2018
ventral wall of dorsal aorta runx1 expression decreased amount, abnormal	epas1a^{bns231/bns231}; epas1b^{bns232/bns232}	standard conditions	Fig. 1 from Gerri et al., 2018
ventral wall of dorsal aorta myb expression decreased amount, abnormal	epas1a^{bns231/bns231}; epas1b^{bns232/bns232}	standard conditions	Fig. 1 from Gerri et al., 2018
hematopoietic progenitor cell differentiation decreased occurrence, abnormal	epas1a^{bns231/bns231}; epas1b^{bns232/bns232}	standard conditions	Fig. 1 from Gerri et al., 2018
whole organism notch1a expression decreased amount, abnormal	epas1a^{bns231/bns231}; epas1b^{bns232/bns232}	control	Fig. 5 from Gerri et al., 2018
whole organism notch1b expression decreased amount, abnormal	epas1a^{bns231/bns231}; epas1b^{bns232/bns232}	control	Fig. 5 from Gerri et al., 2018
hematopoietic system myb expression decreased amount, abnormal	epas1a^{bns231/bns231}; epas1b^{bns232/bns232}	standard conditions	Fig. 1 from Gerri et al., 2018
hematopoietic system runx1 expression decreased amount, abnormal	epas1a^{bns231/bns231}; epas1b^{bns232/bns232}	standard conditions	Fig. 1 from Gerri et al., 2018
whole organism myb expression decreased amount, abnormal	epas1a^{bns231/bns231}; epas1b^{bns232/bns232}	standard conditions	Fig. 4 from Gerri et al., 2018
hemopoiesis decreased occurrence, abnormal	epas1a^{bns231/bns231}; epas1b^{bns232/bns232}	standard conditions	Fig. 1 from Gerri et al., 2018

Citations