TALEN

TALEN1-panx1b

ID

ZDB-TALEN-180608-2

Name

TALEN1-panx1b

Previous Names

None

Target

panx1b (1)

Target Sequence 1

5' - CAGTGGTCTTGAATTG - 3'

Target Sequence 2

5' - CTACCAGAGGATACTT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

This TALEN contains a SNP.

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
nhi7	panx1b
yku2	panx1b

Expression

Gene expression in Wild Types + TALEN1-panx1b

No data available

Phenotype

Phenotype resulting from TALEN1-panx1b

No data available

Phenotype of all Fish created by or utilizing TALEN1-panx1b

Phenotype	Fish	Conditions	Figures
retinal cone cell regulation of calcium ion transmembrane transport decreased process quality, abnormal	panx1b^nhi7/nhi7	standard conditions	Fig. 6 from Cenedese et al., 2017
retinal cone cell cellular response to light stimulus process quality, abnormal	panx1b^nhi7/nhi7	standard conditions	Fig. 4 , Fig. 5 from Cenedese et al., 2017
whole organism egr2a expression increased amount, abnormal	panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 4 from Whyte-Fagundes et al., 2022
whole organism viability, ameliorated	panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 4 from Whyte-Fagundes et al., 2022
whole organism egr2b expression increased amount, abnormal	panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 4 from Whyte-Fagundes et al., 2022
locomotion increased occurrence, ameliorated	panx1b^yku2/yku2	chemical treatment by environment: pentetrazol, chemical treatment by environment: A-438079 hydrochloride hydrate	Fig. 8 from Whyte-Fagundes et al., 2022
whole organism fosab expression amount, ameliorated	panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 4 from Whyte-Fagundes et al., 2022
whole organism ATP increased amount, abnormal	panx1b^yku2/yku2	standard conditions	Fig. 7 from Whyte-Fagundes et al., 2022
whole organism egr4 expression amount, ameliorated	panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 4 from Whyte-Fagundes et al., 2022
optic tectum neuronal action potential increased magnitude, abnormal	panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 1 , Fig. 3 from Whyte-Fagundes et al., 2022
whole organism ATP increased amount, ameliorated	panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 7 from Whyte-Fagundes et al., 2022
locomotion increased occurrence, abnormal	panx1b^yku2/yku2	standard conditions	Fig. 4 from Whyte-Fagundes et al., 2022
locomotion increased occurrence, exacerbated	panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 4 from Whyte-Fagundes et al., 2022
whole organism egr1 expression increased amount, abnormal	panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 4 from Whyte-Fagundes et al., 2022
whole organism bdnf expression increased amount, abnormal	panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 4 from Whyte-Fagundes et al., 2022
locomotion increased occurrence, abnormal	panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 8 from Whyte-Fagundes et al., 2022
whole organism jun expression increased amount, abnormal	panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 4 from Whyte-Fagundes et al., 2022
whole organism cry1a expression decreased amount, abnormal	panx1b^yku2/yku2 (TL)	standard conditions	Figure 3 , Table 2 from Safarian et al., 2021
whole organism increased length, abnormal	panx1b^yku2/yku2 (TL)	standard conditions	Figure 2 from Safarian et al., 2021
whole organism cry5 expression decreased amount, abnormal	panx1b^yku2/yku2 (TL)	standard conditions	Figure 3 , Table 2 from Safarian et al., 2021
whole organism swimming behavior process quality, abnormal	panx1b^yku2/yku2 (TL)	altered light dark cycle	Figure 5 , Figure 6 from Safarian et al., 2021
whole organism detection of light stimulus involved in visual perception process quality, abnormal	panx1b^yku2/yku2 (TL)	altered light dark cycle	Figure 5 , Figure 6 from Safarian et al., 2021
whole organism viability, abnormal	panx1b^yku2/yku2 (TL)	standard conditions	Figure 2 from Safarian et al., 2021
whole organism npas2 expression decreased amount, abnormal	panx1b^yku2/yku2 (TL)	standard conditions	Figure 3 , Table 2 from Safarian et al., 2021
whole organism bmal1b expression decreased amount, abnormal	panx1b^yku2/yku2 (TL)	standard conditions	Figure 3 , Table 2 from Safarian et al., 2021
retina panx1b expression decreased amount, abnormal	panx1b^yku2/yku2 (TL)	standard conditions	Figure 1 from Safarian et al., 2021
whole organism bmal1a expression decreased amount, abnormal	panx1b^yku2/yku2 (TL)	standard conditions	Figure 3 , Table 2 from Safarian et al., 2021
retina panx1b expression decreased distribution, abnormal	panx1b^yku2/yku2 (TL)	standard conditions	Figure 1 from Safarian et al., 2021
whole organism swimming behavior increased process quality, abnormal	panx1b^yku2/yku2 (TL)	constant dark	Figure 4 from Safarian et al., 2021
whole organism cry1b expression decreased amount, abnormal	panx1b^yku2/yku2 (TL)	standard conditions	Figure 3 , Table 2 from Safarian et al., 2021
retinal cone cell regulation of calcium ion transmembrane transport decreased process quality, abnormal	panx1a^nhi6/nhi6; panx1b^nhi7/nhi7	standard conditions	Fig. 6 from Cenedese et al., 2017
retinal cone cell cellular response to light stimulus process quality, abnormal	panx1a^nhi6/nhi6; panx1b^nhi7/nhi7	standard conditions	Fig. 4 , Fig. 5 from Cenedese et al., 2017
whole organism egr2a expression increased amount, abnormal	panx1a^yku1/yku1; panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 4 from Whyte-Fagundes et al., 2022
whole organism egr2b expression increased amount, abnormal	panx1a^yku1/yku1; panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 4 from Whyte-Fagundes et al., 2022
whole organism fosab expression amount, ameliorated	panx1a^yku1/yku1; panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 4 from Whyte-Fagundes et al., 2022
whole organism ATP increased amount, abnormal	panx1a^yku1/yku1; panx1b^yku2/yku2	standard conditions	Fig. 7 from Whyte-Fagundes et al., 2022
whole organism egr4 expression amount, ameliorated	panx1a^yku1/yku1; panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 4 from Whyte-Fagundes et al., 2022
locomotion increased occurrence, abnormal	panx1a^yku1/yku1; panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 4 from Whyte-Fagundes et al., 2022
whole organism egr1 expression increased amount, abnormal	panx1a^yku1/yku1; panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 4 from Whyte-Fagundes et al., 2022
whole organism bdnf expression increased amount, abnormal	panx1a^yku1/yku1; panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 4 from Whyte-Fagundes et al., 2022
whole organism ATP normal amount, ameliorated	panx1a^yku1/yku1; panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 7 from Whyte-Fagundes et al., 2022
optic tectum neuronal action potential magnitude, ameliorated	panx1a^yku1/yku1; panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 1 , Fig. 3 from Whyte-Fagundes et al., 2022
whole organism entpd1 expression increased amount, abnormal	panx1a^yku1/yku1; panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 7 from Whyte-Fagundes et al., 2022
whole organism jun expression increased amount, abnormal	panx1a^yku1/yku1; panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 4 from Whyte-Fagundes et al., 2022
whole organism slc8a2b expression decreased amount, abnormal	panx1a^yku1/yku1; panx1b^yku2/yku2	chemical treatment by environment: pentetrazol	Fig. 7 from Whyte-Fagundes et al., 2022

Citations