TALEN

TALEN1-isl2b

ID

ZDB-TALEN-180110-2

Name

TALEN1-isl2b

Previous Names

None

Target

Target Sequence 1

5' - TCAGATCCACGACCAGTAC - 3'

Target Sequence 2

5' - TGCGTGCCACTCCAGGTCGGGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
uhm1	isl2b

Expression

Gene expression in Wild Types + TALEN1-isl2b

No data available

Phenotype

Phenotype resulting from TALEN1-isl2b

No data available

Phenotype of all Fish created by or utilizing TALEN1-isl2b

Phenotype	Fish	Conditions	Figures
cardiac ventricle decreased size, abnormal	isl2b^uhm1/uhm1	standard conditions	Fig. 3 from Witzel et al., 2017
bulbus arteriosus ltbp3 expression decreased amount, abnormal	isl2b^uhm1/uhm1	standard conditions	Fig. 3 from Witzel et al., 2017
cardiac ventricle cardiac muscle cell decreased amount, abnormal	isl2b^uhm1/uhm1	standard conditions	Fig. 3 from Witzel et al., 2017
heart tube mef2cb expression decreased amount, abnormal	isl2b^uhm1/uhm1	standard conditions	Fig. 3 from Witzel et al., 2017
anterior lateral plate mesoderm mef2ca expression decreased amount, abnormal	isl2b^uhm1/uhm1	standard conditions	Fig. 4 from Witzel et al., 2017
anterior lateral plate mesoderm mef2cb expression decreased amount, abnormal	isl2b^uhm1/uhm1	standard conditions	Fig. 4 from Witzel et al., 2017
anterior lateral plate mesoderm tbx20 expression decreased amount, abnormal	isl2b^uhm1/uhm1	standard conditions	Fig. 4 from Witzel et al., 2017
heart myh7 expression decreased distribution, abnormal	isl2b^uhm1/uhm1	standard conditions	Fig. 3 from Witzel et al., 2017
heart looping decreased occurrence, abnormal	isl2b^uhm1/uhm1	standard conditions	Fig. 3 from Witzel et al., 2017
anterior lateral plate mesoderm hand2 expression decreased amount, abnormal	isl2b^uhm1/uhm1	standard conditions	Fig. 4 from Witzel et al., 2017
heart tube ltbp3 expression decreased amount, abnormal	isl2b^uhm1/uhm1	standard conditions	Fig. 3 from Witzel et al., 2017

Citations