TALEN

TALEN1-hspb7

ID

ZDB-TALEN-131120-1

Name

TALEN1-hspb7

Previous Names

None

Target

hspb7 (1)

Target Sequence 1

5' - CCTCCTCATCTTCATCCTCT - 3'

Target Sequence 2

5' - CCTCGGCTCTTCTCCATGTA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
wcm3	hspb7
wcm4	hspb7

Expression

Gene expression in Wild Types + TALEN1-hspb7

No data available

Phenotype

Phenotype resulting from TALEN1-hspb7

No data available

Phenotype of all Fish created by or utilizing TALEN1-hspb7

Phenotype	Fish	Conditions	Figures
heart cryabb expression increased amount, abnormal	hspb7^wcm3/wcm3	standard conditions	Fig. 2 from Mercer et al., 2018
male organism decreased life span, abnormal	hspb7^wcm3/wcm3	standard conditions	Fig. 3 from Mercer et al., 2018
swimming behavior process quality, abnormal	hspb7^wcm3/wcm3	water flow	Fig. 3 from Mercer et al., 2018
whole organism decreased life span, abnormal	hspb7^wcm3/wcm3	water flow	Fig. 3 from Mercer et al., 2018
heart nppa expression increased amount, abnormal	hspb7^wcm3/wcm3	standard conditions	Fig. 5 from Mercer et al., 2018
heart map1lc3b expression increased amount, abnormal	hspb7^wcm3/wcm3	standard conditions	Fig. 11 from Mercer et al., 2018
sarcomere organization disrupted, abnormal	hspb7^wcm3/wcm3	standard conditions	Fig. 6 from Mercer et al., 2018
heart increased size, abnormal	hspb7^wcm3/wcm3	standard conditions	Fig. 5 from Mercer et al., 2018
heart autophagosome increased amount, abnormal	hspb7^wcm3/wcm3	standard conditions	Fig. 6 from Mercer et al., 2018
liver vacuolated, abnormal	hspb7^wcm3/wcm3	standard conditions	Fig. 5 from Mercer et al., 2018
heart hspb12 expression decreased amount, abnormal	hspb7^wcm3/wcm3	standard conditions	Fig. 5 from Mercer et al., 2018
heart cardiac myofibril disorganized, abnormal	hspb7^wcm3/wcm3	standard conditions	Fig. 6 from Mercer et al., 2018
heart morphology, abnormal	hspb7^wcm3/wcm3; twu34Tg	chemical treatment by environment: chloroquine	Fig. 12 from Mercer et al., 2018
heart development disrupted, abnormal	hspb7^wcm3/wcm3; twu34Tg	chemical treatment by environment: bafilomycin A1	Fig. 12 from Mercer et al., 2018
heart development disrupted, abnormal	hspb7^wcm3/wcm3; twu34Tg	chemical treatment by environment: chloroquine	Fig. 12 from Mercer et al., 2018
heart morphology, abnormal	hspb7^wcm3/wcm3; twu34Tg	chemical treatment by environment: bafilomycin A1	Fig. 12 from Mercer et al., 2018
heart morphology, abnormal	hspb7^wcm3/wcm3; twu34Tg/twu34Tg + CRISPR5-cryabb	standard conditions	Fig. 2 from Mercer et al., 2018
whole organism morphology, abnormal	hspb7^wcm3/wcm3; twu34Tg/twu34Tg + CRISPR5-cryabb	standard conditions	Fig. 2 from Mercer et al., 2018

Citations