PUBLICATION

sox30: a novel zebrafish sox gene expressed in a restricted manner at the midbrain-hindbrain boundary during neurogenesis

Authors
De Martino, S.P., Errington, F., Ashworth, A., Jowett, T., and Austin, C.A.
ID
ZDB-PUB-990628-17
Date
1999
Source
Development genes and evolution   209(6): 357-362 (Journal)
Registered Authors
Austin, Caroline Ann, Jowett, Trevor
Keywords
sox; zebrafish; development; brain; midbrain-hindrain boundary
MeSH Terms
  • Amino Acid Sequence
  • Animals
  • Cloning, Molecular
  • DNA, Complementary/chemistry
  • DNA, Complementary/genetics
  • DNA-Binding Proteins/genetics*
  • Embryo, Nonmammalian/metabolism
  • Evolution, Molecular
  • Gene Expression Regulation, Developmental
  • High Mobility Group Proteins/genetics*
  • In Situ Hybridization
  • Mesencephalon/embryology
  • Mesencephalon/metabolism
  • Molecular Sequence Data
  • Nervous System/embryology
  • Nervous System/metabolism
  • Phylogeny
  • RNA/genetics
  • RNA/metabolism
  • Rhombencephalon/embryology
  • Rhombencephalon/metabolism
  • SOXB2 Transcription Factors
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Sequence Homology, Amino Acid
  • Tissue Distribution
  • Zebrafish
  • Zebrafish Proteins*
(all 28)
PubMed
10370117 Full text @ Dev. Genes Evol.
Abstract
The Sox family of proteins is thought to act to regulate gene expression in a wide variety of developmental processes. Here we describe the cloning of sox30, a novel sox gene from the zebrafish (Danio rerio). In situ hybridization shows that sox30 is expressed in a restricted manner at the boundary between the midbrain and hindbrain during nervous system development. This expression pattern is in direct contrast to that of most other neuronally expressed Sox genes which are expressed throughout the nervous system.
Genes / Markers
Marker Marker Type Name
pax2aGENEpaired box 2a
sox19aGENESRY-box transcription factor 19a
sox21aGENESRY-box transcription factor 21a
1 - 3 of 3
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Figures
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Expression
Phenotype
No data available
Mutations / Transgenics
No data available
Human Disease / Model
No data available
Sequence Targeting Reagents
No data available
Fish
Fish
WT
1 - 1 of 1
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Antibodies
Orthology
Engineered Foreign Genes
No data available
Mapping
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Citation
De Martino, S.P., Errington, F., Ashworth, A., Jowett, T., and Austin, C.A. (1999) sox30: a novel zebrafish sox gene expressed in a restricted manner at the midbrain-hindbrain boundary during neurogenesis. Development genes and evolution. 209(6):357-362.