PUBLICATION
Evolution of the growth hormone-prolactin-somatolactin system in relation to vertebrate tetraploidizations
- Authors
- Ocampo Daza, D., Sundström, G., Larsson, T.A., and Larhammar, D.
- ID
- ZDB-PUB-091016-3
- Date
- 2009
- Source
- Annals of the New York Academy of Sciences 1163: 491-493 (Journal)
- Registered Authors
- Larhammar, Dan, Larsson, Tomas A., Sundström, Görel
- Keywords
- growth hormone, growth hormone receptor, prolactin, prolactin receptor, somatolactin, somatolactin receptor, gene duplication, tetraploidization
- MeSH Terms
-
- Animals
- Chromosomes/genetics
- Evolution, Molecular*
- Humans
- Phylogeny*
- Pituitary Hormones/classification*
- Pituitary Hormones/genetics*
- Ploidies*
- Vertebrates/classification*
- Vertebrates/genetics*
- PubMed
- 19456396 Full text @ Ann N Y Acad Sci
Citation
Ocampo Daza, D., Sundström, G., Larsson, T.A., and Larhammar, D. (2009) Evolution of the growth hormone-prolactin-somatolactin system in relation to vertebrate tetraploidizations. Annals of the New York Academy of Sciences. 1163:491-493.
Abstract
Gene sequences from several species representing major vertebrate groups were used to create phylogenetic trees for the growth hormone family of peptide hormones as well as the growth hormone receptor family. These analyses show that both the peptide and receptor families were formed through local duplications in early vertebrate evolution and chromosome duplications.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping