PUBLICATION

Zebrafish genetics and vertebrate heart formation

Authors
Stainier, D.Y.R.
ID
ZDB-PUB-010219-2
Date
2001
Source
Nature reviews. Genetics   2: 39-48 (Review)
Registered Authors
Stainier, Didier
Keywords
none
MeSH Terms
  • Animals
  • Caenorhabditis/genetics
  • Cell Differentiation
  • Drosophila/genetics
  • Heart/embryology*
  • Morphogenesis
  • Mutation
  • Myocardium/cytology
  • Vertebrates/embryology*
  • Vertebrates/genetics*
  • Zebrafish/embryology*
  • Zebrafish/genetics*
(all 12)
PubMed
11253067 Full text @ Nat. Rev. Genet.
Abstract
Forward-genetic analyses in Drosophila and Caenorhabditis elegans have given us unprecedented insights into many developmental mechanisms. To study the formation of organs that contain cell types and structures not present in invertebrates, a vertebrate model system amenable to forward genetics would be very useful. Recent work shows that a newly initiated genetic approach in zebrafish is already making significant contributions to understanding the development of the vertebrate heart, an organ that contains several vertebrate-specific features. These and other studies point to the utility of the zebrafish system for studying a wide range of vertebrate-specific processes.
Genes / Markers
No data available
Figures
No images available
Expression
Phenotype
No data available
Mutations / Transgenics
No data available
Human Disease / Model
No data available
Sequence Targeting Reagents
No data available
Fish
No data available
Antibodies
Orthology
Engineered Foreign Genes
No data available
Mapping
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Citation
Stainier, D.Y.R. (2001) Zebrafish genetics and vertebrate heart formation. Nature reviews. Genetics. 2:39-48.