Person

Ngai, John

Person ID: ZDB-PERS-970113-1
Email: jngai@socrates.berkeley.edu
URL: http://mcb.berkeley.edu/faculty/NEU/ngaij.html
Affiliation: Ngai Lab
Address: Department of Molecular & Cell Biology University of California 269 Life Sciences Addition Berkeley, CA 94720-3200 USA
Country: United States
Phone: (510) 642-9885
Fax: (510) 643-2685
ORCID ID

Biography and Research Interest

Olfaction presents an interesting and complex problem in perception: how does the olfactory apparatus of vertebrates detect and discriminate thousands of odors? Our approach to elucidating the mechanisms of olfactory discrimination involves the characterization of odorant receptors and the neural pathways that they activate. We are also interested in the developmental mechanisms responsible for specifying odorant receptor expression in olfactory neurons and the pathfinding of these cells' axons to their appropriate targets.

Publications

Non-Zebrafish Publications

Brunet, L.J., G.H. Gold, and J. Ngai. 1996. General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel. Neuron 17, 681-693.

Speca, D.J., D.M. Lin, P.W. Sorensen, E.Y. Isacoff, J. Ngai, and A.H. Dittman. 1999. Functional identification of a goldfish odorant receptor. Neuron 23, 487-498.

Lin, D.M., F. Wang, G. Lowe, G. H. Gold, R. Axel, J. Ngai, and L. Brunet. 2000. Formation of precise synaptic connections in the olfactory bulb occurs in the absence of odorant-evoked neuronal activity. Neuron 26, 69-80.