Person
Karasik, David
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Biography and Research Interest
The primary objective of our research is to understand the biology behind the function and pathology of complex physiological systems and metabolic processes. Our research focuses on identifying genes involved in the genetic variation of complex traits, including bone mass, muscle (lean) mass, and fatty liver.
Non-Zebrafish Publications
Hsu, Y-H, Estrada, K, Evangelou, E … Rivadeneira F, Kiel DK, Karasik D. Meta-analysis of Genome-Wide Association Studies Reveals Genetic Variants for Hip Bone Geometry. J Bone & Mineral Research 2019 34(7):1284-129
Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X... Karasik D ... Kiel DP, Lunetta KL, Slagboom PE, Murabito JM. A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nat Commun. 2019, 14;10(1):3669.
Granot-Hershkovitz E, Wu P, Karasik D, Peter I, Peloso G, Levy, Vasan R, Cupples L.A., Liu CT, Meigs J, Siscovick D, Dupuis J, Friedlander Y, and Hochner H. Searching for Parent-of-origin effects on cardiometabolic traits in imprinted genomic regions. European Journal of Human Genetics 2020: 28(5):646-655
Trajanoska K, Lotta J. Seppala, Carolina Medina-Gomez, Yi-Hsiang Hsu ... Karasik D ... DP. Kiel, AG. Uitterlinden, JR.B. Perry, N. van der Velde, FR. Day, F Rivadeneira. Genetic basis of falling risk susceptibility in the UK Biobank Study. Communications Biology 2020 [Paper #543]
Jones G*, K. Trajanoska*, A. J Santanasto*, N. Stringa*, C-L Kuo*, JL Atkins* … J M Murabito*, G A Kuchel*, L Ferrucci*, D Melzer*, D Karasik*, F Rivadeneira*, DP Kiel*, LC Pilling*. Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women. Nat Commun. 2021