Biography and Research Interest

Umea University, Sweden (Ph.D.)

National Human Genome Research Institute, NIH (Postdoc)

Publications

Non-Zebrafish Publications

LaFave MC, Varshney GK, Burgess SM. GeIST: a pipeline for mapping integrated DNA elements. Bioinformatics. 2015 Oct 1;31(19):3219-21. doi: 10.1093/bioinformatics/btv350. Epub 2015 Jun 6.


Chandler RJ, LaFave MC, Varshney GK, Trivedi NS, Carrillo-Carrasco N, Senac JS, Wu W, Hoffmann V, Elkahloun AG, Burgess SM, Venditti CP. Vector design
influences hepatic genotoxicity after adeno-associated virus gene therapy. J Clin Invest. 2015 Feb;125(2):870-80. doi: 10.1172/JCI79213. Epub 2015 Jan 20.

Walia JS, Altaleb N, Bello A, Kruck C, LaFave MC, Varshney GK, Burgess SM, Chowdhury B, Hurlbut D, Hemming R, Kobinger GP, Triggs-Raine B. Long-term
correction of sandhoff disease following intravenous delivery of rAAV9 to mouse neonates. Mol Ther. 2015 Mar;23(3):414-22. doi: 10.1038/mt.2014.240.

Lafave MC, Varshney GK, Gildea DE, Wolfsberg TG, Baxevanis AD, Burgess SM. MLV integration site selection is driven by strong enhancers and active promoters. Nucleic Acids Res. 2014 Jan 23. [Epub ahead of print] PubMed PMID: 24464997.

Chen L, Stuart L, Ohsumi TK, Burgess S, Varshney GK, Dastur A, Borowsky M, Benes C, Lacy-Hulbert A, Schmidt EV. Transposon activation mutagenesis as a screening tool for identifying resistance to cancer therapeutics. BMC Cancer. 2013 Feb 27;13:93. doi: 10.1186/1471-2407-13-93. PubMed PMID: 23442791; PubMed Central PMCID: PMC3598783.

Yamazaki Y, Schonherr C, Varshney GK, Dogru M, Hallberg B, Palmer RH. Goliath family E3 ligases regulate the recycling endosome pathway via VAMP3 ubiquitylation. EMBO J. 2013 Feb 20;32(4):524-37. doi: 10.1038/emboj.2013.1. Epub 2013 Jan 25. PubMed PMID: 23353890; PubMed Central PMCID: PMC3579141.

Eriksson T, Varshney G, Aspenstrom P, Palmer RH. Characterisation of the role of Vrp1 in cell fusion during the development of visceral muscle of Drosophila melanogaster. BMC Dev Biol. 2010 Aug 11;10:86. doi: 10.1186/1471-213X-10-86. PubMed PMID: 20701765; PubMed Central PMCID: PMC2931478.

Shirinian M, Popovic M, Grabbe C, Varshney G, Hugosson F, Bos H, Rehmann H, Palmer RH. The Rap1 guanine nucleotide exchange factor C3G is required for preservation of larval muscle integrity in Drosophila melanogaster. PLoS One. 2010 Mar 3;5(3):e9403. doi: 10.1371/journal.pone.0009403. Erratum in: PLoS One. 2010;5(3). doi: 10.1371/annotation/c3ebafa0-1531-4e9f-ab3a-660db7b8dcd2.

Shirinian M, Varshney G, Loren CE, Grabbe C, Palmer RH. Drosophila Anaplastic Lymphoma Kinase regulates Dpp signalling in the developing embryonic gut. Differentiation. 2007 Jun;75(5):418-26. Epub 2007 Feb 5. PubMed PMID: 17286600.


Varshney GK, Palmer RH. The bHLH transcription factor Hand is regulated by Alk in the Drosophila embryonic gut. Biochem Biophys Res Commun. 2006 Dec 29;351(4):839-46. Epub 2006 Oct 30. PubMed PMID: 17094947.

Varshney GK, Singh US, Mishra DP, Kumar A. Immuno-pathotyping of Karnal bunt (Tilletia indica) isolates of wheat using anti-mycelial antibodies. Indian J Exp Biol. 2003 Mar;41(3):255-61. PubMed PMID: 15267157.


Englund C, Loren CE, Grabbe C, Varshney GK, Deleuil F, Hallberg B, Palmer RH. Jeb signals through the Alk receptor tyrosine kinase to drive visceral muscle fusion. Nature. 2003 Oct 2;425(6957):512-6. PubMed PMID: 14523447.