Person
Wythe, Joshua
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Biography and Research Interest
2023-Current
Associate Professor
Dept. of Neuroscience, Dept of Cell Biology
University of Virginia School of Medicine
2020-2023
Associate Professor
Dept. of Neurosurgery, Dept of Integrative Physiology
Cardiovascular Research Institute
Baylor College of Medicine
2014-2020
Assistant Professor
Dept. of Neurosurgery, Dept of Integrative Physiology
Cardiovascular Research Institute
Baylor College of Medicine
2012-2014
Staff Scientist
UCSF
Gladstone Institute of Cardiovascular Disease
2011-2012
Research Scientist
UCSF
Gladstone Institute of Cardiovascular Disease
Benoit Bruneau Lab
Postdoc
2008-2011
UCSF
Gladstone Insitute of Cardiovascular Disease
Benoit Bruneau Lab
PhD
2007
University of Utah
Oncological Sciences
Dean Y. Li Lab
M.S., M.A.
2001
Miami University
Botany / History
Makaroff and Kiss Labs
Associate Professor
Dept. of Neuroscience, Dept of Cell Biology
University of Virginia School of Medicine
2020-2023
Associate Professor
Dept. of Neurosurgery, Dept of Integrative Physiology
Cardiovascular Research Institute
Baylor College of Medicine
2014-2020
Assistant Professor
Dept. of Neurosurgery, Dept of Integrative Physiology
Cardiovascular Research Institute
Baylor College of Medicine
2012-2014
Staff Scientist
UCSF
Gladstone Institute of Cardiovascular Disease
2011-2012
Research Scientist
UCSF
Gladstone Institute of Cardiovascular Disease
Benoit Bruneau Lab
Postdoc
2008-2011
UCSF
Gladstone Insitute of Cardiovascular Disease
Benoit Bruneau Lab
PhD
2007
University of Utah
Oncological Sciences
Dean Y. Li Lab
M.S., M.A.
2001
Miami University
Botany / History
Makaroff and Kiss Labs
Non-Zebrafish Publications
Liu Q, Hu T, He L, Huang X, Tian X, Zhang H, He L, Pu W, Zhang L, Sun H, Fang J, Yu Y, Duan S, Hu C, Hui L, Zhang H, Quertermous T, Xu Q, Red-Horse K, Wythe JD, Zhou B (2015). Genetic targeting of sprouting angiogenesis using Apln-CreER. Nat Commun. PMID: 25597280
He L, Tian X, Zhang H, Wythe JD, Zhou B (2014). Fabp4-CreER lineage tracing reveals two distinctive coronary vascular populations. J Cell Mol Med. PMID: 25265869
Devine WP, Wythe JD, George M, Koshiba-Takeuchi K, Bruneau BG (2014).Early patterning and specification of cardiac progenitors in gastrulating mesoderm. Elife. PMID: 25296024
Qian L, Wythe JD, Liu J, Cartry J, Vogler G, Mohapatra B, Otway RT, Huang Y, King IN, Maillet M, Zheng Y, Crawley T, Taghli-Lamallem O, Semsarian C, Dunwoodie S, Winlaw D, Harvey RP, Fatkin D, Towbin JA, Molkentin JD, Srivastava D, Ocorr K, Bruneau BG, Bodmer R. (2011) Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. J Cell Biol (7):1181-96. PMID: 21690310
Jones CA, London NR, Chen H, Park KW, Sauvaget D, Stockton RA, Wythe JD, Suh W, Larrieu-Lahargue F, Mukouyama YS, Lindblom P, Seth P, Frias A, Nishiya N, Ginsberg MH, Gerhardt H, Zhang K, Li DY (2008) Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability. Nat. Med (4):448-53. Erratum in: Nat Med. 2008 May;14(5):585. PMID: 18345009
Karnik SK, Wythe JD, Sorensen L, Brooke BS, Urness LD, Li DY (2003) Elastin induces myofibrillogenesis via a specific domain, VGVAPG. Matrix Biol. 22(5):409-25. PMID: 14614988
Karnik SK, Brooke BS, Bayes-Genis A, Sorensen L, Wythe JD, Schwartz RS, Keating MT, Li DY (2003) A critical role for elastin signaling in vascular morphogenesis and disease. Development, 130(2):411-23. PMID: 12466207