Person
Shin, Donghun
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Biography and Research Interest
My goals are to understand the molecular and cellular mechanisms regulating liver development and regeneration. In particular, I am interested in molecular mechanisms underlying liver progenitor cell-driven liver regeneration.
Non-Zebrafish Publications
Shin D, Anderson DJ (2005), Isolation of arterial-specific genes by subtractive hybridization reveals molecular heterogeneity among arterial endothelial cells. Dev Dyn, 233(4):1589-604.Mukouyama YS, Shin D, Britsch S, Taniguchi M, Anderson DJ (2002), Sensory nerves determine the pattern of arterial differentiation and blood vessel branching in the skin. Cell, 109(6):693-705.
Shin D, Garcia-Cardena G, Hayashi S, Gerety S, Asahara T, Stavrakis G, Isner J, Folkman J, Gimbrone MA Jr, Anderson DJ (2001), Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization. Dev Biol, 230(2):139-50.
Yoo SJ, Kim HH, Shin DH, Lee CS, Seong IS, Seol JH, Shimbara N, Tanaka K, Chung CH (1998), Effects of the cys mutations on structure and function of the ATP-dependent HslVU protease in Escherichia coli. The Cys287 to Val mutation in HslU uncouples the ATP-dependent proteolysis by HslvU from ATP hydrolysis. J Biol Chem, 273(36):22929-35.
Seol JH, Yoo SJ, Shin DH, Shim YK, Kang MS, Goldberg AL, Chung CH (1997), The heat-shock protein HslVU from Escherichia coli is a protein-activated ATPase as well as an ATP-dependent proteinase. Eur J Biochem, 247(3):1143-50.
Yoo SJ, Seol JH, Shin DH, Rohrwild M, Kang MS, Tanaka K, Goldberg AL, Chung CH (1996), Purification and characterization of the heat shock proteins HslV and HslU that form a new ATP-dependent protease in Escherichia coli. J Biol Chem, 271(24):14035-40.
Shin DH, Yoo SJ, Shim YK, Seol JH, Kang MS, Chung CH (1996), Mutational analysis of the ATP-binding site in HslU, the ATPase component of HslVU protease in Escherichia coli. FEBS Lett, 398(2-3):151-4.