Biography and Research Interest

My research interests are ATP receptors involved in purinergic signaling and the development of the peripheral sensory nervous system.

Publications

Non-Zebrafish Publications

Pratt, E. B., Brink, T. S., Bergson, P., Voigt, M.M. and Cook, S.P. (2005) Use-dependent inhibition of P2X3 receptors by nanomolar agonist. J. Neurosci. 25:7359-7365

Li, Z., Migita, K., Samways, D.S.-K., Voigt, M.M. and Egan, T.M. (2004) Gain and loss of channel function by alanine-substitutions in the transmembrane segments of the rat ATP-gated P2X2 receptor. J. Neurosci. 24:9378-9386.

Egan, T.M., Cox, J.A. and Voigt, M.M. (2004) Molecular structure of P2X receptors. in Current Topics in Medicinal Chemistry 4(8):821-829 (Jacobsen, K., ed.) Academic Press, San Diego, CA

Egan, T.M. and Voigt, M.M. (2003) Relating the structure of ATP-gated ion channel receptors to their function. in Current Topics in Membranes, 53:183-202 (Schwiebert, E.M., ed.). Academic Press, San Diego, CA

Haines, W.R., Migita, K., Cox, J.A., Egan T.M. and Voigt, M.M. (2001) The first transmembrane domain of the P2X receptor subunit participates in the agonist-induced gating of the channel. J. Biol. Chem. 276:32793-32798.

Migita, K., Haines, W.R., Voigt, M.M. and Egan, T.M. (2001) Polar residues of the second transmembrane domain influence cation permeability of the ATP-gated P2X2 receptor. J.Biol. Chem. 276:30934-30941.

Khakh, B.S., Burnstock, G., Kennedy C., King, B.F., North, R.A., Seguela, P., Voigt, M. and P.P.A. Humphrey (2001) International Union of Pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits. Pharmacol. Rev. 53:107-118.

Haines, W.R., Voigt, M.M., Migita, K., Torres, G.E. and Egan, T.M. (2001) On the contribution of the first transmembrane domain to whole-cell current through an ATP-gated ionotropic P2X receptor.J. Neurosci. 21:5885-5892.

Cox, J.A., Barmina, O. and Voigt, M.M. (2001) Gene structure, chromosomal localization, cDNA cloning and expression of the mouse ATP-gated ionotropic receptor P2X5 subunit. Gene: 270:145-152.

Haines, W.R., Torres, G.T., Voigt, M.M and Egan, T.M. (1999) Properties of the novel ATP-gated ionotropic receptor composed of the P2X1 and P2X5 isoforms. Mol. Pharmacol. 56:720-727.

Torres, G., Egan, T.M. and Voigt, M.M. (1999) Identification of a domain involved in ATP-gated ionotropic P2X receptor subunit assembly. J. Biol. Chem. 274:22359-22365.

Torres, G., Egan, T.M. and Voigt, M.M. (1999) Hetero-oligomeric assembly of P2X receptor subunits: specificities exist with regard to possible partners. J. Biol. Chem.274:6653-6659.

Torres, G., Haines, W.R, Egan, T.M. and Voigt, M.M. (1998) Co-expression of the P2X1 and P2X5 receptor subunits reveals a novel ATP-gated ion channel. Mol. Pharmacol. 54:989-993.

Torres, G., Egan, T.M. and Voigt, M.M. (1998) N-linked glycosylation is essential for the functional expression of the recombinant P2X2 receptor. Biochemistry 37:14845-14851.

Torres, G., Egan, T.M. and Voigt, M.M. (1998) Topological analysis of the ATP-gated ionotropic P2X2 receptor subunit. FEBS Lett. 425:19-23.

Egan, T., Haines, W. and Voigt, M.M. (1998) Identification of a domain contributing to the ion-conducting pore of the ATP-gated P2X2 receptors identified by the substituted cysteine accessibility method. J. Neurosci. 18:2350-2359.