Morpholino

MO1-polg

ID

ZDB-MRPHLNO-210921-2

Name

MO1-polg

Previous Names

Target

Sequence

5' - AGCTGTGAGCTGACAAACCTTAGGT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Splice-blocking MO.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-polg

Expressed Gene	Anatomy	Figures
polg	whole organism	Fig. 1 from Facchinello et al., 2021

Phenotype

Phenotype resulting from MO1-polg

Phenotype	Fish	Figures
atrium increased size, abnormal	WT + MO1-polg	Fig. 1 , Fig. 6 from Facchinello et al., 2021
hypoxia-inducible factor-1alpha signaling pathway increased occurrence, abnormal	ia21Tg + MO1-polg	Fig. 1 from Facchinello et al., 2021
positive regulation of CREB transcription factor activity increased occurrence, abnormal	zf3275Tg + MO1-polg	Fig. S1 from Facchinello et al., 2021
skeletal muscle mitochondrion fused with skeletal muscle mitochondrion, abnormal	WT + MO1-polg	Fig. 1 from Facchinello et al., 2021
skeletal muscle mitochondrion swollen, abnormal	WT + MO1-polg	Fig. 1 from Facchinello et al., 2021
whole organism polg expression decreased amount, abnormal	WT + MO1-polg	Fig. 1 from Facchinello et al., 2021
whole organism decreased size, abnormal	WT + MO1-polg	Fig. 1 from Facchinello et al., 2021

Phenotype of all Fish created by or utilizing MO1-polg

Phenotype	Fish	Conditions	Figures
whole organism polg expression decreased amount, abnormal	WT + MO1-polg	standard conditions	Fig. 1 from Facchinello et al., 2021
skeletal muscle mitochondrion swollen, abnormal	WT + MO1-polg	standard conditions	Fig. 1 from Facchinello et al., 2021
whole organism decreased size, abnormal	WT + MO1-polg	standard conditions	Fig. 1 from Facchinello et al., 2021
skeletal muscle mitochondrion fused with skeletal muscle mitochondrion, abnormal	WT + MO1-polg	standard conditions	Fig. 1 from Facchinello et al., 2021
atrium increased size, abnormal	WT + MO1-polg	standard conditions	Fig. 1 from Facchinello et al., 2021
hypoxia-inducible factor-1alpha signaling pathway increased occurrence, abnormal	ia21Tg + MO1-polg	standard conditions	Fig. 1 from Facchinello et al., 2021
atrium increased size, abnormal	ia300Tg + MO1-polg	standard conditions	Fig. 6 from Facchinello et al., 2021
positive regulation of CREB transcription factor activity increased occurrence, abnormal	zf3275Tg + MO1-polg	standard conditions	Fig. S1 from Facchinello et al., 2021

Citations