Morpholino

MO2-bdnf

ID

ZDB-MRPHLNO-190412-1

Name

MO2-bdnf

Previous Names

None

Target

Sequence

5' - GGTCATCACTCTTCTAACCTGTTGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Splice-blocking MO.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO2-bdnf

Expressed Gene	Anatomy	Figures
bdnf	whole organism	Fig. 5 from Endlich et al., 2018
nphs2	whole organism	Fig. 5 from Endlich et al., 2018

Phenotype

Phenotype resulting from MO2-bdnf

Phenotype	Fish	Figures
whole organism nphs2 expression decreased amount, abnormal	WT + MO2-bdnf	Fig. 5 from Endlich et al., 2018
whole organism bdnf expression decreased amount, abnormal	WT + MO2-bdnf	Fig. 5 from Endlich et al., 2018

Phenotype of all Fish created by or utilizing MO2-bdnf

Phenotype	Fish	Conditions	Figures
whole organism nphs2 expression decreased amount, abnormal	WT + MO2-bdnf	standard conditions	Fig. 5 from Endlich et al., 2018
whole organism bdnf expression decreased amount, abnormal	WT + MO2-bdnf	standard conditions	Fig. 5 from Endlich et al., 2018
podocyte decreased amount, abnormal	mitfa^w2/w2; mpv17^a9/a9; li1Tg + MO2-bdnf	standard conditions	Fig. 6 from Endlich et al., 2018
renal glomerulus increased size, abnormal	mitfa^w2/w2; mpv17^a9/a9; li1Tg + MO2-bdnf	standard conditions	Fig. 6 from Endlich et al., 2018
pronephric capsular space increased size, abnormal	mitfa^w2/w2; mpv17^a9/a9; li1Tg + MO2-bdnf	standard conditions	Fig. 6 from Endlich et al., 2018
pronephric glomerulus morphology, abnormal	mitfa^w2/w2; mpv17^a9/a9; li1Tg + MO2-bdnf	standard conditions	Fig. 6 from Endlich et al., 2018
pericardium edematous, abnormal	mitfa^w2/w2; mpv17^a9/a9; lri500Tg + MO2-bdnf	standard conditions	Fig. 5 from Endlich et al., 2018
blood EGFP expression decreased amount, abnormal	mitfa^w2/w2; mpv17^a9/a9; lri500Tg + MO2-bdnf	standard conditions	Fig. 5 from Endlich et al., 2018
whole organism decreased life span, abnormal	mitfa^w2/w2; mpv17^a9/a9; lri500Tg + MO2-bdnf	standard conditions	Fig. 5 from Endlich et al., 2018

Citations