Morpholino

MO3-mecp2

ID
ZDB-MRPHLNO-171016-1
Name
MO3-mecp2
Previous Names
None
Target
Sequence
5' - TCCGCTCTCTGCGGCGGCCATTTTT - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
Translation-blocking MO.
Genome Resources
None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO3-mecp2
Expressed Gene Anatomy Figures
bdnf Fig. 5 from Nozawa et al., 2017
Phenotype
Phenotype resulting from MO3-mecp2
Phenotype Fish Figures
CaP motoneuron axon decreased branchiness, abnormal WT + MO3-mecp2 Fig. 2 from Nozawa et al., 2017
CaP motoneuron axon morphology, abnormal WT + MO3-mecp2 Fig. 2 from Nozawa et al., 2017
CaP motoneuron axonogenesis disrupted, abnormal WT + MO3-mecp2 Fig. 2 from Nozawa et al., 2017
motor neuron axon guidance disrupted, abnormal WT + MO3-mecp2 Fig. 2,  Fig. 4 from Nozawa et al., 2017
myotome neuromuscular junction ab-sv2 labeling increased distribution, abnormal WT + MO3-mecp2 Fig. 5 from Nozawa et al., 2017
myotome presynaptic density increased amount, abnormal WT + MO3-mecp2 Fig. 5 from Nozawa et al., 2017
neuromuscular junction development disrupted, abnormal WT + MO3-mecp2 Fig. 7 from Nozawa et al., 2017
Rohon-Beard neuron axon decreased branchiness, abnormal WT + MO3-mecp2 Fig. 1 from Nozawa et al., 2017
Rohon-Beard neuron axon decreased length, abnormal WT + MO3-mecp2 Fig. 1 from Nozawa et al., 2017
secondary motor neuron axon decreased branchiness, abnormal WT + MO3-mecp2 Fig. 4 from Nozawa et al., 2017
secondary motor neuron axon morphology, abnormal WT + MO3-mecp2 Fig. 4 from Nozawa et al., 2017
swimming behavior process quality, abnormal WT + MO3-mecp2 Fig. 4 from Nozawa et al., 2017
thigmotaxis disrupted, abnormal WT + MO3-mecp2 Fig. 3 from Nozawa et al., 2017
whole organism bdnf expression increased amount, abnormal WT + MO3-mecp2 Fig. 5 from Nozawa et al., 2017
Phenotype of all Fish created by or utilizing MO3-mecp2
Phenotype Fish Conditions Figures
Rohon-Beard neuron axon decreased length, abnormal WT + MO3-mecp2 standard conditions Fig. 1 from Nozawa et al., 2017
myotome presynaptic density increased amount, abnormal WT + MO3-mecp2 standard conditions Fig. 5 from Nozawa et al., 2017
CaP motoneuron axon morphology, abnormal WT + MO3-mecp2 standard conditions Fig. 2 from Nozawa et al., 2017
thigmotaxis disrupted, abnormal WT + MO3-mecp2 standard conditions Fig. 3 from Nozawa et al., 2017
Rohon-Beard neuron axon decreased branchiness, abnormal WT + MO3-mecp2 standard conditions Fig. 1 from Nozawa et al., 2017
whole organism bdnf expression increased amount, abnormal WT + MO3-mecp2 standard conditions Fig. 5 from Nozawa et al., 2017
neuromuscular junction development disrupted, abnormal WT + MO3-mecp2 standard conditions Fig. 7 from Nozawa et al., 2017
myotome neuromuscular junction ab-sv2 labeling increased distribution, abnormal WT + MO3-mecp2 standard conditions Fig. 5 from Nozawa et al., 2017
secondary motor neuron axon decreased branchiness, abnormal WT + MO3-mecp2 standard conditions Fig. 4 from Nozawa et al., 2017
swimming behavior process quality, abnormal WT + MO3-mecp2 standard conditions Fig. 4 from Nozawa et al., 2017
secondary motor neuron axon morphology, abnormal WT + MO3-mecp2 standard conditions Fig. 4 from Nozawa et al., 2017
CaP motoneuron axonogenesis disrupted, abnormal WT + MO3-mecp2 standard conditions Fig. 2 from Nozawa et al., 2017
motor neuron axon guidance disrupted, abnormal WT + MO3-mecp2 standard conditions Fig. 2,  Fig. 4 from Nozawa et al., 2017
CaP motoneuron axon decreased branchiness, abnormal WT + MO3-mecp2 standard conditions Fig. 2 from Nozawa et al., 2017
Rohon-Beard neuron axon decreased length, abnormal WT + MO1-bdnf + MO3-mecp2 standard conditions Fig. 8 from Nozawa et al., 2017
Rohon-Beard neuron axon decreased branchiness, abnormal WT + MO1-bdnf + MO3-mecp2 standard conditions Fig. 8 from Nozawa et al., 2017
thigmotaxis disrupted, abnormal WT + MO1-bdnf + MO3-mecp2 standard conditions Fig. 8 from Nozawa et al., 2017
Citations
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