Morpholino

MO2-ins

ID

ZDB-MRPHLNO-160331-1

Name

MO2-ins

Previous Names

None

Target

ins (1)

Sequence

5' - CCTCTACTTGACTTTCTTACCCAGA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Splice-blocking MO.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO2-ins

Expressed Gene	Anatomy	Figures
pdx1	endoderm primary islet whole organism	Fig. 4 from Ye et al., 2016

Phenotype

Phenotype resulting from MO2-ins

Phenotype	Fish	Figures
endoderm EGFP expression decreased amount, abnormal	jh1Tg + MO2-ins	Fig. 4 from Ye et al., 2016
pancreatic A cell differentiation decreased occurrence, abnormal	WT + MO2-ins	Fig. 5 from Ye et al., 2016
pancreatic B cell increased amount, abnormal	jh1Tg; jh2Tg + MO2-ins	Fig. 2 from O'Hare et al., 2016
pancreatic B cell increased area, abnormal	jh1Tg; jh2Tg + MO2-ins	Fig. 1 from O'Hare et al., 2016
pancreatic B cell mCherry expression increased distribution, abnormal	jh1Tg; jh2Tg + MO2-ins	Fig. S3 from O'Hare et al., 2016
primary islet pancreatic B cell decreased amount, abnormal	jh2Tg + MO2-ins	Fig. S11 from O'Hare et al., 2016
type B pancreatic cell differentiation premature, abnormal	jh1Tg + MO2-ins	Fig. 4 from Ye et al., 2016
whole organism pdx1 expression increased amount, abnormal	WT + MO2-ins	Fig. 4 from Ye et al., 2016

Phenotype of all Fish created by or utilizing MO2-ins

Phenotype	Fish	Conditions	Figures
pancreatic A cell differentiation decreased occurrence, abnormal	WT + MO2-ins	standard conditions	Fig. 5 from Ye et al., 2016
whole organism pdx1 expression increased amount, abnormal	WT + MO2-ins	standard conditions	Fig. 4 from Ye et al., 2016
endoderm EGFP expression decreased amount, abnormal	jh1Tg + MO2-ins	standard conditions	Fig. 4 from Ye et al., 2016
type B pancreatic cell differentiation premature, abnormal	jh1Tg + MO2-ins	standard conditions	Fig. 4 from Ye et al., 2016
primary islet pancreatic B cell decreased amount, abnormal	jh2Tg + MO2-ins	standard conditions	Fig. S11 from O'Hare et al., 2016
pancreatic B cell increased amount, abnormal	jh1Tg; jh2Tg + MO2-ins	standard conditions	Fig. 2 from O'Hare et al., 2016
pancreatic B cell increased area, abnormal	jh1Tg; jh2Tg + MO2-ins	standard conditions	Fig. 1 from O'Hare et al., 2016
pancreatic B cell mCherry expression increased distribution, abnormal	jh1Tg; jh2Tg + MO2-ins	standard conditions	Fig. S3 from O'Hare et al., 2016
pancreatic B cell increased amount, abnormal	s892Tg + MO2-ins	standard conditions	Fig. 4 , Fig. 5 from Ye et al., 2016
pancreatic A cell decreased amount, abnormal	s892Tg + MO2-ins	standard conditions	Fig. 5 from Ye et al., 2016
pancreatic B cell regeneration increased occurrence, abnormal	s892Tg + MO2-ins	chemical ablation: pancreatic B cell, chemical treatment by environment: metronidazole	Fig. 6 from Ye et al., 2016
regenerating tissue pancreatic B cell increased amount, abnormal	s892Tg + MO2-ins	chemical ablation: pancreatic B cell, chemical treatment by environment: metronidazole	Fig. 6 from Ye et al., 2016
insulin secreting cell increased amount, abnormal	s892Tg + MO2-ins	standard conditions	Fig. 5 from Ye et al., 2016
primary islet pdx1 expression increased amount, abnormal	s892Tg + MO2-ins	standard conditions	Fig. 4 from Ye et al., 2016
endoderm pdx1 expression increased amount, abnormal	s892Tg + MO2-ins	standard conditions	Fig. 4 from Ye et al., 2016
glucagon secreting cell decreased amount, abnormal	s892Tg + MO2-ins	standard conditions	Fig. 5 from Ye et al., 2016
pancreatic A cell regeneration decreased occurrence, abnormal	s892Tg + MO2-ins	chemical ablation: pancreatic B cell, chemical treatment by environment: metronidazole	Fig. 6 from Ye et al., 2016

Citations