Morpholino

MO1-ldlra

ID
ZDB-MRPHLNO-150312-1
Name
MO1-ldlra
Previous Names
None
Target
Sequence
5' - AGATCACATTTCATTTCTTACAGCA - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
Splice-blocking MO.
Genome Resources
None
Target Location
Genome Build: GRCz11Chromosome: 3
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO1-ldlra
Expressed Gene Anatomy Figures
abca1b Fig. S6 from O'Hare et al., 2014
hmgcra Fig. S6 from O'Hare et al., 2014
ldlra Fig. 1 from O'Hare et al., 2014
pcsk9 Fig. S6 from O'Hare et al., 2014
srebf2 Fig. S6 from O'Hare et al., 2014
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Phenotype
Phenotype resulting from MO1-ldlra
Phenotype Fish Figures
caudal vein cholesterol increased amount, abnormal TU + MO1-ldlra Fig. 3 from Montasser et al., 2018
cholesterol homeostasis process quality, abnormal WT + MO1-ldlra Fig. 2,  Fig. 3,  Fig. S6 from O'Hare et al., 2014
liver fatty, abnormal WT + MO1-ldlra Fig. S7 from O'Hare et al., 2014
liver increased size, abnormal WT + MO1-ldlra Fig. S7 from O'Hare et al., 2014
posterior cardinal vein fatty, abnormal WT + MO1-ldlra Fig. 3 from O'Hare et al., 2014
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Phenotype of all Fish created by or utilizing MO1-ldlra
Phenotype Fish Conditions Figures
caudal vein cholesterol increased amount, abnormal TU + MO1-ldlra control Fig. 3 from Montasser et al., 2018
whole organism low-density lipoprotein cholesterol increased amount, abnormal TU + MO1-ldlra control Fig. 3 from Montasser et al., 2018
caudal vein cholesterol increased amount, abnormal TU + MO1-ldlra high cholesterol Fig. 3 from Montasser et al., 2018
whole organism low-density lipoprotein cholesterol increased amount, abnormal TU + MO1-ldlra high cholesterol Fig. 3 from Montasser et al., 2018
liver increased size, abnormal WT + MO1-ldlra standard conditions Fig. S7 from O'Hare et al., 2014
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Citations
TSV
1 - 2 of 2
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