Morpholino

MO2-orai1b

ID

ZDB-MRPHLNO-120312-2

Name

MO2-orai1b

Previous Names

MO-ORAI1 (1)
ORAI1 exon 1 (1)

Target

orai1b (1)

Sequence

5' - AAACAGCGCGGAGACTCACCATTGC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Splice-blocking MO.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO2-orai1b

Expressed Gene	Anatomy	Figures
nppa	atrium cardiac ventricle	Fig. 3 from Völkers et al., 2012

Phenotype

Phenotype resulting from MO2-orai1b

Phenotype	Fish	Figures
blood circulation decreased rate, abnormal	WT + MO2-orai1b	Fig. 1 from Völkers et al., 2012
cardiac muscle cell sarcomere decreased amount, abnormal	WT + MO2-orai1b	Fig. 2 from Völkers et al., 2012
cardiac muscle cell sarcomere decreased thickness, abnormal	WT + MO2-orai1b	Fig. 2 from Völkers et al., 2012
cardiac muscle cell Z disc malformed, abnormal	WT + MO2-orai1b	Fig. 2 from Völkers et al., 2012
detection of muscle stretch process quality, abnormal	WT + MO2-orai1b	Fig. 3 from Völkers et al., 2012
heart edematous, abnormal	WT + MO2-orai1b	Fig. 1 from Völkers et al., 2012
heart physical object quality, abnormal	WT + MO2-orai1b	Fig. 3 from Völkers et al., 2012
heart contraction decreased magnitude, abnormal	WT + MO2-orai1b	Fig. 1 from Völkers et al., 2012
heart contraction decreased rate, abnormal	WT + MO2-orai1b	Fig. 1 from Völkers et al., 2012
myotome myofibril detached from vertical myoseptum, abnormal	WT + MO2-orai1b	Fig. 2 from Völkers et al., 2012
sarcomere organization decreased process quality, abnormal	WT + MO2-orai1b	Fig. 2 from Völkers et al., 2012
skeletal muscle cell myofibril disorganized, abnormal	WT + MO2-orai1b	Fig. 2 from Völkers et al., 2012
skeletal muscle cell Z disc decreased amount, abnormal	WT + MO2-orai1b	Fig. 2 from Völkers et al., 2012
vertical myoseptum malformed, abnormal	WT + MO2-orai1b	Fig. 2 from Völkers et al., 2012

Phenotype of all Fish created by or utilizing MO2-orai1b

Phenotype	Fish	Conditions	Figures
myotome myofibril detached from vertical myoseptum, abnormal	WT + MO2-orai1b	standard conditions	Fig. 2 from Völkers et al., 2012
cardiac muscle cell sarcomere decreased amount, abnormal	WT + MO2-orai1b	standard conditions	Fig. 2 from Völkers et al., 2012
heart physical object quality, abnormal	WT + MO2-orai1b	standard conditions	Fig. 3 from Völkers et al., 2012
skeletal muscle cell myofibril disorganized, abnormal	WT + MO2-orai1b	standard conditions	Fig. 2 from Völkers et al., 2012
vertical myoseptum malformed, abnormal	WT + MO2-orai1b	standard conditions	Fig. 2 from Völkers et al., 2012
heart contraction decreased rate, abnormal	WT + MO2-orai1b	standard conditions	Fig. 1 from Völkers et al., 2012
skeletal muscle cell Z disc decreased amount, abnormal	WT + MO2-orai1b	standard conditions	Fig. 2 from Völkers et al., 2012
sarcomere organization decreased process quality, abnormal	WT + MO2-orai1b	standard conditions	Fig. 2 from Völkers et al., 2012
detection of muscle stretch process quality, abnormal	WT + MO2-orai1b	standard conditions	Fig. 3 from Völkers et al., 2012
blood circulation decreased rate, abnormal	WT + MO2-orai1b	standard conditions	Fig. 1 from Völkers et al., 2012
cardiac muscle cell Z disc malformed, abnormal	WT + MO2-orai1b	standard conditions	Fig. 2 from Völkers et al., 2012
cardiac muscle cell sarcomere decreased thickness, abnormal	WT + MO2-orai1b	standard conditions	Fig. 2 from Völkers et al., 2012
heart contraction decreased magnitude, abnormal	WT + MO2-orai1b	standard conditions	Fig. 1 from Völkers et al., 2012
heart edematous, abnormal	WT + MO2-orai1b	standard conditions	Fig. 1 from Völkers et al., 2012

Citations