Morpholino

MO2-pknox1.1

ID

ZDB-MRPHLNO-061010-1

Name

MO2-pknox1.1

Previous Names

Target

Sequence

5' - GCCACTGCCAACACTGGGACATTAT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

The morpholino sequence shown in Deflorian et al. 2004 (Dev. 131:613-627) contains a typo. The corrected sequence is shown here.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO2-pknox1.1

No data available

Phenotype

Phenotype resulting from MO2-pknox1.1

Phenotype	Fish	Figures
brain apoptotic, abnormal	WT + MO2-pknox1.1	Fig. 3 from Deflorian et al., 2004
brain morphology, abnormal	WT + MO2-pknox1.1	Fig. 3 from Deflorian et al., 2004
brain segmentation disrupted, abnormal	WT + MO2-pknox1.1	Fig. 4 from Deflorian et al., 2004
cell death increased occurrence, abnormal	WT + MO2-pknox1.1	Fig. 3 from Deflorian et al., 2004
CNS interneuron decreased amount, abnormal	WT + MO2-pknox1.1	Fig. 5 from Deflorian et al., 2004
ethmoid cartilage decreased size, abnormal	WT + MO2-pknox1.1	Fig. 6 from Deflorian et al., 2004
ethmoid cartilage deformed, abnormal	WT + MO2-pknox1.1	Fig. 6 from Deflorian et al., 2004
facial nerve motor nucleus mislocalised, abnormal	WT + MO2-pknox1.1	Fig. 5 from Deflorian et al., 2004
hindbrain development disrupted, abnormal	WT + MO2-pknox1.1	Fig. 4 from Deflorian et al., 2004
rhombomere neuron organization quality, abnormal	WT + MO2-pknox1.1	Fig. 5 from Deflorian et al., 2004
trabecula cranii decreased size, abnormal	WT + MO2-pknox1.1	Fig. 6 from Deflorian et al., 2004
trabecula cranii deformed, abnormal	WT + MO2-pknox1.1	Fig. 6 from Deflorian et al., 2004
whole organism viability, abnormal	WT + MO2-pknox1.1	text only from Deflorian et al., 2004

Phenotype of all Fish created by or utilizing MO2-pknox1.1

Phenotype	Fish	Conditions	Figures
trabecula cranii deformed, abnormal	WT + MO2-pknox1.1	standard conditions	Fig. 6 from Deflorian et al., 2004
ethmoid cartilage deformed, abnormal	WT + MO2-pknox1.1	standard conditions	Fig. 6 from Deflorian et al., 2004
ethmoid cartilage decreased size, abnormal	WT + MO2-pknox1.1	standard conditions	Fig. 6 from Deflorian et al., 2004
brain segmentation disrupted, abnormal	WT + MO2-pknox1.1	standard conditions	Fig. 4 from Deflorian et al., 2004
rhombomere neuron organization quality, abnormal	WT + MO2-pknox1.1	standard conditions	Fig. 5 from Deflorian et al., 2004
brain morphology, abnormal	WT + MO2-pknox1.1	standard conditions	Fig. 3 from Deflorian et al., 2004
brain apoptotic, abnormal	WT + MO2-pknox1.1	standard conditions	Fig. 3 from Deflorian et al., 2004
hindbrain development disrupted, abnormal	WT + MO2-pknox1.1	standard conditions	Fig. 4 from Deflorian et al., 2004
whole organism viability, abnormal	WT + MO2-pknox1.1	standard conditions	text only from Deflorian et al., 2004
cell death increased occurrence, abnormal	WT + MO2-pknox1.1	standard conditions	Fig. 3 from Deflorian et al., 2004
trabecula cranii decreased size, abnormal	WT + MO2-pknox1.1	standard conditions	Fig. 6 from Deflorian et al., 2004
CNS interneuron decreased amount, abnormal	WT + MO2-pknox1.1	standard conditions	Fig. 5 from Deflorian et al., 2004
facial nerve motor nucleus mislocalised, abnormal	WT + MO2-pknox1.1	standard conditions	Fig. 5 from Deflorian et al., 2004

Citations