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Figure Caption
Fig. 5 1D 1H STD NMR spectra for compound 5x recorded at an Hsp90β:ligand ratio of 1:100. The molecular structure illustrates the proton nomenclature and the colour-coded relative degrees of saturation of individual non-overlapping protons. The STD amplification factors were normalised to the intensity of the signal with the largest STD effect. The reference STD spectrum (top) with proton assignment and the difference STD spectrum (bottom) are shown. The unassigned proton signals between 3.5 and 3.8 ppm belong to protein buffer with glycerol. The spectra are not to scale.
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