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Fig. 2 Six weeks of E2 supplementation mitigates diet-induced obesity in both sexes. Female weight (A) and length gain (B) over the feeding period. Male weight gain (D) and body length gain (E) over the feeding period. Terminal blood glucose was collected after an overnight fast (C, F). Error bars indicate mean ± SEM, n = 5–7 for female study and n = 4–7 for male study. Statistical tables for these data are provided in Supplementary Figures S6–S15. Tables indicate statistically significant differences in body weight and length gain. *p < 0.05, **p < 0.01.
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