ZFIN Image: Lee et al., 2024, Figure 5

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Figure Caption

Figure 5

Inflammation-induced activity of enteric neurons. (A–C) Intestinal images of 10 dpf larvae labeled with anti-Hu (green) and anti-5-HT (red) antibodies. Arrows indicate 5-HT+/Hu+ neurons in the intestine. Scale bar: 50 μM. (D–F) Intestinal images of 10 dpf larvae labeled with anti-Hu (green) and anti-pERK (red) antibodies. Arrows indicate pERK+/Hu+ neurons in the intestine. Scale bar: 50 μM. (G) Comparison of the number (#) of Hu+ enteric neurons among all groups: n = 25 for control group; n = 30 for light-stress group; n = 38 for light-stress/B. longum group. (H) Comparison of the number (#) of 5-HT+/Hu+ serotonin enteric neurons among all groups: n = 12 for control group; n = 17 for light-stress group; n = 15 for light-stress/B. longum group. (I) Comparison of the number (#) of pERK+/Hu+ enteric neurons among all groups: n = 13 for control group; n = 20 for light-stress group; n = 21 for light-stress/B. longum group. ns, not significant; * p < 0.05; ** p < 0.01.

Acknowledgments

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