ZFIN Image: Claude-Taupin et al., 2023, Fig. 9

Image

Figure Caption

Fig. 9 YAP reactivation upon chronic kidney disease is correlated with autophagy inhibition.

a Representative images of kidney sections subjected to immunohistochemistry for YAP from controls (n = 5) and patients with diabetic nephropathy (DKD, n = 5) Scale bars, 30 µm. b Quantification of YAP nuclear levels in the renal tubules. Data show the mean ± s.e.m.; n = 5. two-sided t-test. c Representative images of kidney sections subjected to immunohistochemistry for LC3 and LAMP1 from controls and patients with diabetic nephropathy (n = 5) Scale bars, 30 µm. d Quantification of colocalization between LC3 and LAMP1 in the renal tubules. Data show the mean ± s.e.m.; n = 4 (controls) and n = 5 (diabetic nephropathy). two-sided t-test. Source data are provided as a Source Data file.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.