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Fig. 4 A simple theoretical gene regulatory network reproduces temporal changes in progenitor competence Distribution of each Atoh7+ division in time (event plots) from 28 hpf in Atoh7 morphants, Ptf1a morphants and double Atoh7/Ptf1a morphants. Coloured violin plots indicate different fates and grey violin plots show all neurogenic divisions analysed. Time in hpf. Probability estimation from lineage data in (A) for each fate outcome at the time at which an Atoh7+ division occurs in Atoh7 morphants, Ptf1a morphants and double Atoh7/Ptf1a morphants. Time in hpf. Mean (dark line) and 95% confidence interval (thick transparent stripe) are plotted. Simulation scenario A run using a simple GRN tested based on the hypothesis formulated based on the probability estimation plots in (B). Mean (dark line) and 95% confidence interval (thick transparent stripe) are plotted. Simulation scenario B run using a simple GRN in which inhibitory effects of two or more TFs are summed (green lines), and tested based on the hypothesis formulated based on the probability estimation plots in (B). Mean (dark line) and 95% confidence interval (thick transparent stripe) are plotted. Probability estimation from lineage data in Fig 1I for each fate outcome at the time at which an Atoh7+ division occurs in controls. Time in hpf. Mean (dark line) and 95% confidence interval (thick transparent stripe) are plotted. Prediction of fate shares in the control situation using Simulation Scenario A (left) and Simulation Scenario B (right). Mean (dark line) and 95% confidence interval (thick transparent stripe) are plotted.