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FIGURE 5
Perturbation of fos causes epithelial abnormalities. (A–H) Examination of Keratin-4 expressing cells showed abnormal arrangements of peridermal epithelial cells around the oral cavity in both crispants (B and F) and morphants (C and G) compared to controls at both 3dpf (A and D) and 5dpf (E and H). Periderm cell size was quantified and both crispants and morphants (minimum of n = 60 cells per condition; n≥5 embryos at each timepoint) statistical test showed reduced perioral cell area at 3dpf (I) and 5dpf (J) compared to controls. UIC, uninjected control; F0, crispant; MO, morpholino; MM, mismatch.
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Full text @ Front Cell Dev Biol