ZFIN Image: Sveinsdóttir et al., 2022, Fig. 4

Image

Figure Caption

Fig. 4 Effects of moxonidine in spontaneous alternation rodent assay.

A significant difference was found between mice exposed to scopolamine and naïve mice (saline) in which scopolamine-exposed mice showed decrease in spontaneous alterations. Treatment with donepezil and atomoxetine rescued this effect. Moxonidine also rescued this effect in mice in a dose-dependent manner, showing significantly higher spontaneous alterations in mice treated with 0.3 mg/kg and 1 mg/kg treatment but no significant differences were observed between mice treated with 0.1 mg/kg moxonidine compared to scopolamine treated mice. * denote significant differences.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Neuropsychopharmacology