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Figure 1
The amount of NAMPT protein and PARylation increased in lesional skin of AD patients. Representative images and analysis of biopsy sections from healthy (n = 10) and AD (n = 6) skin biopsies immunostained with anti-NAMPT (A,B) and anti-PAR (C,D). The mean ± SEM of each group is shown. p values were calculated using the nonparametric Mann–Whitney test, **** p ≤ 0.0001. Scale bar is 50 μm in all panels. CL: cornified layer; D: dermis; SL: spinous layer.
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