ZFIN Image: Frey et al., 2022, Fig. 6

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Figure Caption

Fig. 6 Fig. 6. Cell proliferation in damaged RPE of fluke-infected eyes of threespine stickleback. Sections (7 μm thickness) were counterstained with DAPI to show positions of nuclei associated with the RPE. A-D. Region of healthy RPE (from Grimsa): brightfield (BF) image (A), PCNA (B), and DAPI (C) staining. No PCNA-positive nuclei are present in this region of RPE (D; merged image; three DAPI-positive nuclei are indicated with arrows). E-H. Region of damaged RPE (from Grimsa): brightfield image (E), PCNA (F), and DAPI (G) staining. Several PCNA-positive nuclei are associated with the damaged RPE (H; merged image), two are indicated with arrows. Scale bar: A (applies to all), 20 μm.

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Reprinted from Experimental Eye Research, 225, Frey, R.A., Barrett, L.M., Parkin, L., Blakeley, B., Ålund, M., Byford, G., Euhus, A., Tsarnas, C., Boughman, J.W., Stenkamp, D.L., Eye flukes (Diplostomum spp.) damage retinal tissue and may cause a regenerative response in wild threespine stickleback fish, 109298, Copyright (2022) with permission from Elsevier. Full text @ Exp. Eye. Res.