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Figure 4
Role of Tfap2 transcription factors in DE segment differentiation in the zebrafish pronephros. (A) trm mutants exhibit reductions (indicated by blue boxes) in the expression of transcripts that encode DE segment solute transporters, such as slc12a1. (B) Tfap2a is a requisite for discrete aspects of DE differentiation, but is not required for features such as polarity establishment and ciliogenesis. Adapted from Ref. [148].
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