FIGURE 7

The Cone Photoreceptor Cell Activity is Enhanced in gjd2b ^−/− /Cx35.1^−/− Larvae. (A) Overview of the experimental procedure. Burst activity was assessed for (B, C) Light-ON responses and (D, E) Light-OFF responses. Both WT and gjd2b ^−/− /Cx35.1 ^−/− larvae readily detected light transitions indicative of visual functionality. In comparison to the WT, gjd2b ^−/− /Cx35.1^−/− larvae were hyperactive, suggesting that they were more sensitive to light stimulation. No significant difference was found for light-OFF responses. The statistical significance was determined by a Mann-Whitney test. The sample size (N) was 48 for wild-type and gjd2b ^−/− /Cx35.1^−/− larvae.