ZFIN Image: Bearce et al., 2022, Figure 2

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Figure 2

Urp1 and Urp2 are required for proper adult spine morphology.

(A–C) Lateral views of microcomputed tomography reconstitutions of wild-type (A), urp1^∆P;urp2^∆P (B) and uts2r3^b1436 (C) mutants at 3 mpf. (D) Cobb angle measurements for individual fish in the sagittal plane for urp1^∆P;urp2^∆P and uts2r3^b1436 mutants. Circles represent angles for individual curves. (E-E’) Total Cobb angles with each circle representing an individual fish. The mean ± s.d. is shown. (G’) is the data from G parsed for sex. p-Values are given from two-tailed unpaired student’s t tests. (F) The position of curve apex is plotted and shows that most curves are in caudal vertebrae. n=9 and 8 for urp1^∆P;urp2^∆P and uts2r3^b1436 mutants, respectively.

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Acknowledgments

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