ZFIN Image: Kang et al., 2022, Figure 3

Image

Figure Caption

Figure 3

KO of GCGR in zebrafish increased glucagon expression in α-cells.A and B, the plots show the expression of glucagon genes (A) and their regulators (B). The color scale ranges gray to blue corresponding to expression level from low to high; all plots are based on cell clusters shown in Fig. 1B. C, the violin plots show gcga and gcgb relative expression in α-cells from control and gcgr^−/− zebrafish. D, heatmap of differentially expressed genes (DEGs) of gcgr^−/− compared to control cells; the color scale ranges red to blue corresponding to expression level from low to high. E, pathway enrichment analysis of DEGs between gcgr^−/− and control cells. GCGR, glucagon receptor.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Biol. Chem.