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Figure 7 Inhibitory effect of resveratrol on doxorubicin-induced stimulation of osteoclasts. The ctsk reporter zebrafish transgenic line (Tg[ctsk:DsRed]) at 25 dpf was exposed to different concentrations of resveratrol (RES, 75 µM and 100 µM) alone or together with Doxorubicin (DOX, 17.2 µM) for 96 h and ctsk signal was measured in the head area. Quantification of fluorescence intensity between the treatment groups performed using fluorescent images acquired with the same parameters and analyzed with ImageJ (A), and ctsk-positive cells in the head of fish from the different treatment groups (B). One-way ANOVA, Tukey’s multiple comparisons test, *— p ≤ 0.05, **—p ≤ 0.01, ****—p ≤ 0.0001.