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Figure 3 Inhibition of doxorubicin-induced osteoclast differentiation by resveratrol. RAW 264.7 cells were cultured for 4 days with M-CSF (30 ng/mL) and RANKL (50 ng/mL) and treated with resveratrol (RES) and doxorubicin (DOX) alone or combined. Levels of mRNA expression for Oc-stamp (A), Rank (B) Trap (C), Ctsk (D), Nfatc1 (E) and Nf-kb p105 (F) were analyzed by qPCR. One-way ANOVA, Tukey’s multiple comparisons test, *—p ≤ 0.05, **—p ≤ 0.01, ***—p ≤ 0.001, ****—p ≤ 0.0001.
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Full text @ Int. J. Mol. Sci.