Fig. 5
Expression of lamprey adorb in contiguous segments of the nose is distinctly different from that observed in jawed vertebrates. ISH was performed in horizontal cross-sections of the olfactory organ of L. fluviatilis using NBT/BCIP for visualizing adorb1 (A–D) and tarl7a (aka Lor3) expression (E). Adorb1 is expressed in a contiguous region adjacent to the olfactory sensory area (A, B), in some cases close to the inner tip (C) and rarely in intermediate zones (D) of the OE. In contrast, a known olfactory receptor (Lor3, Berghard and Dryer 1998), is sparsely distributed in the olfactory sensory area (E). Scale bar (A) 300 µm, (B–E) 100 µm.