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Fig. 4
Silencing PCSK9 influences the expression of genes of the innate immune response in HepG2 cells. The relative expression levels of PCSK9, HAMP, C7, SOCS3, TNF, TNFAIP3, C6 and LDLRAP1 were determined in control (n = 3) and PCSK9 siRNA (n = 3) transfected HepG2 cells using qPCR. Gene expression levels were normalized to GAPDH expression and target genes were run once as technical duplicates. A 2-tailed t test was used for statistics
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