ZFIN Image: Yamashita et al., 2022, FIGURE 2

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Figure Caption

FIGURE 2

The effect of pancuronium on end-plate currents in fast and slow muscle fibers. (A) Fluorescent image of 4 dpf Tg (hb9:tTAad, TRE:ChRFR-TagRFP) zebrafish. Motor neurons specifically expressed channelrhodopsin fused with TagRFP. (B) Representative current traces from fast (top) and slow (bottom) muscle fibers in response to the light stimulation in the presence of pancuronium, whose concentration in the solution is indicated above the traces. Note some of the traces have notches, which result from the non-overlapping time course of inputs from multiple motor neurons innervating the muscle cell. (*p < 0.05, Student’s t-test with bonferroni correction) (C) The effect of pancuronium on EPC charges. Light-evoked EPCs were recorded in the varying concentration of pancuronium.

Acknowledgments

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