Fig. 4

Fig. 4 Fig 4. Endocardial WSS for a single intra-trabecular space, or groove, under the various scenarios considered. (A) Velocity vectors in a simulation conducted with the individual intra-trabecular space (orange arrow) joined to the main ventricular chamber for a 3 dpf zebrafish embryonic ventricle, which is the “Baseline” scenario in B. (B) Contour maps of the end-systolic WSS of the single intra-trabecular space under the different scenarios. In the “No Ventricle” scenario, the ventricular main chamber was detached from the intra-trabecular space, and replaced with a zero-reference pressure boundary condition. In the “No Ventricle, No Deformation” scenario, deformational motions, due to the contraction, were further removed from the “No Ventricle” scenario, but not the full translational motions. In the “No Ventricle, No Translation” scenario, translational motions were further removed from the “No Ventricle scenario”, but not the deformational motions. (C) Mean and standard deviation of the WSS (n = 6) for each scenario, calculated by averaging both spatially (over entire endocardial surface) and temporally (over entire cardiac cycle). * p<0.05.