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Fig. 2 Bioinformatic analysis. (A–C) Heat maps displaying the expression level of genes up- or down-regulated in the negative-, low-, and high-fli1+ cells, with each of the two populations compared separately. Genes for which the fold change was bigger than two and FDR was less than 0.05 were included in the heat maps. (D and E) Bar plots showing enrichment Q- values of functional terms in genes up-regulated (D) or down-regulated (E) in high-fli1+ compared with low-fli1+. Up-regulated or down-regulated genes were defined based on EdgeR FDR cutoff 1e-5.
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Full text @ Proc. Natl. Acad. Sci. USA