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Figure 6
Cognitive impairments are attenuated by prophylactic Shh activation. (A) Histogram quantifying the number of trials required for associative learning assay of undamaged and either untreated or Shh-modulated sTBI fish at 1, 3, 5, 7 and 14 dpi (n = 9 fish per control/experimental group). (B) Quantification of immediate and delayed recall of undamaged, sTBI, and sTBI/PUR fish (n = 9 fish per control/experimental group). Statistical analyses were performed with a one-way ANOVA followed by Tukey’s multiple comparison post hoc test, # p < 0.05, ## p < 0.01.
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