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Fig 3
Treatment of vmat2 larvae with a dopamine agonist or precursor.
Homozygous vmat2 (HOM) larvae were treated with three different concentrations (1μM, 10μM and 100μM) of pramipexole (A, C) or L-dopa (B, D) and compared to untreated larvae (naïve). Pramipexole and L-Dopa did not significantly alter the peak velocity at the onset of lights-off (A, B). Pramipexole (C) reduced the distance moved during lights-on significantly for all three concentrations whereas L-Dopa (D) increased it significantly for 1μM and 10μM. Naïve wild type (WT) larvae are included in the data for visual comparison. For values and statistics see Tables Tables11 and and22.
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